经典点据阅读的题型

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SAT写作经典例子之化学家巴斯德

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Pasteur

LouisPasteurwasbornonDecember27,1822inDole,intheregionofJura,France.Hisdiscoverythatmostinfectiousdiseasesarecausedbygerms,knownasthe"germtheoryofdisease",isoneofthemostimportantinmedicalhistory.Hisworkbecamethefoundationforthescienceofmicrobiology,andacornerstoneofmodernmedicine.

Pasteur'sphenomenalcontributionstomicrobiologyandmedicinecanbesummarizedaollows.First,hechampionedchangesinhospitalpracticestominimizethespreadofdiseasebymicrobes.Second,hediscoveredthatweakenedformsofamicrobecouldbeusedasanimmunizationagainstmorevirulentformsofthemicrobe.Third,Pasteurfoundthatrabieswastranittedbyagentssoalltheycouldnotbeseenunderamicroscope,thusrevealingtheworldofviruses.Asaresulthedevelopedtechniquestovaccinatedogsagainstrabies,andtotreathumansbittenbyrabiddogs.Andfourth,Pasteurdeveloped"pasteurization",aprocessbywhichharmfulmicrobesinperishablefoodproductsaredestroyedusingheat,withoutdestroyingthefood.

HisWorks

EachdiscoveryinthebodyofPasteur'sworkrepresentsalinkinanuninterruptedchain,beginningwithmolecularasymmetryandendingwithhisrabiesprophylaxis,bywayofhisresearchinfermentation,silkworm,wineandbeerdiseases,asepsisandvaccines.

FromCrystallographytoMolecularAsymmetry

In1847attheageof26,Pasteurdidhiirstworkonmolecularasymmetry,bringingtogethertheprinciplesofcrystallography,chemistryandoptics.Heformulatedafundamentallaw:asymmetrydifferentiatestheanicworldfromthemineralworld.Inotherwords,asymmetricmoleculesarealwaystheproductoflifeforces.Hisworkbecamethebasisofanewscience--stereochemistry.

ResearchonFermentationandSpontaneousGeneration

AttherequestofadistillernamedBigofromthenorthofFrance,Pasteurbegantoexaminewhyalcoholbeescontaminatedwithundesirablesubstancesduringfermentation.Hesoondemonstratedthateachsortoffermentationislinkedtotheexistenceofaspecificmicroaniorferment--alivingbeingthatonecanstudybycultivationinanappropriate,sterilemedium.Thisinsightisthebasisofmicrobiology.

Pasteurdeliveredthefatalblowtothedoctrineofspontaneousgeneration,thetheoryheldfor20centuriesthatlifecouldarisespontaneouslyinanicmaterials.Healsodevelopedagermtheory.Atthesametime,hediscoveredtheexistenceoflifewithoutoxygen:

"Fermentationistheconsequenceoflifewithoutair".Thediscoveryofanaerobiclifepedthewayforthestudyofgermsthatcausesepticemiaandgangrene,amongotherinfections.ThankstoPasteur,itbecamepossibletodevisetechniquestokillmicrobesandtocontrolcontamination.


Techniqueof"Pasteurization"

EmperorNapoleonIIIaskedPasteurtoinvestigatethediseasesafflictingwinewhichwerecausingconsiderableeconomiclossestothewineindustry.PasteurwenttoineyardinArboisin1864tostudythisproblem.Hedemonstratedthatwinediseasesarecausedbymicroanisthatcanbekilledbyheatingthewineto55deg.Cforseveralminutes.Appliedtobeerandmilk,thisprocess,called"pasteurization",sooncameintousethroughouttheworld.

ResearchonInfectiousDiseasesAfflictingManandAnimal

In1865,PasteurbegantostudythesilkwormdiseasesthatwerecripplingthesilkindustryinFrance.Hediscoveredtheinfectiousagentsandrevealedthemannerinwhichtheseagentsaretranitted--bycontagionandhereditaryprinciple--andhowtopreventthem.Elaboratingonhisstudyoffermentation,hecouldnowconfirmthateachdiseaseiscausedbyaspecificmicrobeandthatthesemicrobesareforeignelements.Withthisknowledge,Pasteurwasabletoestablishthebasicrulesofsterilizationorasepsis.Preventingcontagionandinfection,hiethodofsterilizationrevolutionizedsurgeryandobstetrics.

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From1877to1887,Pasteuremployedthesefundamentalsofmicrobiologyinthebattleagainstinfectiousdiseases.Hewentontodiscoverthreebacteriaresponsibleforhumanillnesses:staphylococcus,streptococcusandpneumococcus.

TreatmentandPreventionofRabies

LouisPasteurdiscoveredthemethodfortheattenuationofvirulentmicroanisthatisthebasisofvaccination.Hedevelopedvaccinesagainstchickencholera,anthraxandswineerysipelas.Aftermasteringhiethodofvaccination,heappliedthisconcepttorabies.OnJuly6,1885,Pasteurtestedhispioneeringrabiestreatmentonmanforthefirsttime:theyoungJosephMeisterwassed.

TheCreationofthePasteurInstitute

OnMarch1,1886,PasteurpresentedtheresultsofhisrabiestreatmenttotheAcademyofSciencesandcalledforthecreationofarabiesvaccinecenter.Anextensive,internationalpublicdriveforfundinancedtheconstructionofthePasteurInstitute,aprivate,state-approvedinstituterecognizedbythePresidentofFrance,JulesGrévy,in1887andinauguratedbyhissuccessorSadiCarnotin1888.InaccordancewithPasteur'swishes,theInstitutewaoundedasaclinicforrabiestreatment,aresearchcenterforinfectiousdiseaseandateachingcenter.

The66-year-oldscientistwentontodedicatethelastsevenyearsofhislifetotheInstitutethatstillbearshisname.Duringthisperiod,Pasteuralsocametoknowthejoysoffameandwashonoredthroughouttheworldwithprestigiousdecorations.

Hisworkwascontinuedandamplifiedthroughouttheworldbyhisdisciples,thePasteuriens.

AManofFreedomandRigor

Pasteur'sworkisnotsimplythesumofhisdiscoveries.Italsorepresentstherevolutionofscientificmethodology.Pasteursuperimposedtwoindisputablerulesofmodernresearch:thefreedomofcreativeimaginationnecessarilysubjectedtorigorousexperimentation.Hewouldteachhisdisciples:

"Donotputforwardanythingthatyoucannotprovebyexperimentation"

LouisPasteurwasahumanist,alwaysworkingtowardstheimprovementofthehumancondition.Hewasafreemanwhoneverhesitatedtotakeissuewiththeprevailingyetfalseideasofhistime.

Heascribedparticularimportancetothespreadofknowledgeandtheapplicationsofresearch.

Inthescientist'slifetime,PasteurientheoryandmethodwereputintousewellbeyondthebordersofFrance.

Fullyawareoftheinternationalimportanceofhiswork,Pasteur'sdisciplesdispersedthemselveswherevertheirassistancewasneeded.In1891,thefirstForeignInstitutPasteurwaoundedinSaigon(todayHoChiMinhCity,Vietnam)launchingwhatwastobeeastinternationalworkofInstitutsPasteur.

Becausehechangedtheworldforever,hishomelandandtheworldhelongconsideredhimabenefactorofhumanity.

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